Quebec – Montreal – L'Île-Des-Soeurs
Corporation
www.aegera.com
Quebec
Montreal
L'Île-Des-Soeurs
Corporation
active
- #61607;Clinical stage biotechnology company focused on developing drugs that control apoptosis to address major unmet medical needs.
- #61607;Multiple programs in development to induce apoptosis to kill cancer cells and to prevent apoptosis to save injured neuronal cells: o AEG35156 targets the key anti-apoptotic protein XIAP, and is currently in multiple Phase 1/2 clinical trials for the treatment of solid tumors and leukemia;
o LS104 is a novel, non-ATP competitive, small molecule tyrosine kinase inhibitor targeting therapeutically significant kinases including JAK2 and Bcr-Abl. LS104 is currently being tested in a Phase 1 clinical trial in combination with cytarabine in patients with hematological malignancies and myeloproliferative disorders.
o AEG40826 is a potent small molecule that antagonizes the activity of key Inhibitor of Apoptosis Proteins (IAPs). AEG40826 has completed definitive preclinical toxicology studies and a Phase 1 clinical trial in oncology will be initiated in Q1/2008;
o AEG33773 is a novel, orally bioavailable small molecule JNK pathway inhibitor, being developed to treat painful diabetic neuropathy; AEG33773 is currently in definitive preclinical toxicology testing and will enter a Phase 1 clinical trial in Q1/2008.
Country of Ownership: Canada
Year Established: 2000
Exporting: No
Primary Industry (NAICS): 541710 - Research and Development in the Physical, Engineering and Life Sciences
Alternate Industries (NAICS): 541990 - All Other Professional, Scientific and Technical Services
Primary Business Activity: Services
Number of Employees: 40
Services:
Research - development, Biotechnology
Technology:
More details available upon request.
Bechard Robert
Berendt Michael J.
Bérubé Linda
Boudreau Mathieu
Cook Jeremy Curnock
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